Theresa Stocks: A stochastic model for the normal tissue complication probability (NTCP) and applications
Time: Wed 2016-10-19 15.15
Location: Room 306, House 6, Kräftriket, Department of Mathematics, Stockholm University
Participating: Theresa Stocks (matstat, SU)
Abstract: The normal tissue complication probability (NTCP) is a measure for the estimated side effects of a given radiation treatment schedule for cancer patients. Here we use a stochastic logistic birth death process to define an organ and patient specific NTCP. We emphasize an asymptotic simplification which relates the NTCP to the solution of a logistic differential equation. This framework is based on simple modelling assumptions and it prepares a framework for the use of the NTCP model in clinical practice. As example, we consider side effects of prostate cancer brachytherapy. The presentation is based on Stocks, Hillen, Gong and Burger (2016).